You should never argue with the interviewer even though there may be genuine points of contention. There are some effective tactics for approaching disagreements and getting your point across without provoking an argument.
Generally speaking, interviewers tend to believe that people behave in interviews the same way as they do at work. Whilst this is evidently not necessarily true, because the interview is an unusual and sometimes tense environment, it does confirm that you should never become confrontational with the interviewer. The golden rule in an interview is to never argue, but to talk them round.
If you disagree with something that your interviewer says, check your understanding first. Ask a question or questions to clarify their meaning as this demonstrates that you are keen to clarify the precise facts, ahead of making your point.
Whilst the interviewer is in control during an interview, this does not mean that you should agree with everything they say. Some questions may be asked to see how you handle disagreement and you do not want to appear weak or characterless.
When you are stating your opinion, do so in a way that is polite and gracious. This demonstrates that you do not see any major issue between you and the interviewer; you simply have different views. Remember, this is how the interviewer will picture you behaving in the working environment.